Course Title: |
BIOFLUID MECHANINCS |
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Code: |
EPE_002 |
Semester: | Spring |
Weekly teaching hours | CREDITS (ECTS) | |
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Lecture: | 2 | 5 |
SYLLABUS |
Fundamentals of Fluid Mechanics
Intrinsic Fluid Properties, Hydrostatics Macroscopic Balances of Mass and Momentum, Microscopic Balances of Mass and Momentum, Bernoulli Equation Dimensional Analysis. Fluid Mechanics in a Straight Tube, Boundary Layer Separation Introduction to Mechanics of Materials. Linear elastic solid and linear viscous fluid. Viscoelasticity, elastic moduli, viscosity. Analysis of Thin-Walled Cylindrical Tubes. Analysis of Thick-Walled Cylindrical Tubes Heart. Cardiac Valves, Systemic Circulation, Coronary Circulation Pulmonary Circulation and Gas Exchange in the Lungs, Cerebral and Renal Circulations Microcirculation. Regulation of the Circulation. Atherosclerosis Rheology of Blood and Vascular Mechanics Rheology of Blood. Linear flux of blood, Casson equation, Rauleaux formation condition. Static and Steady Flow Models Hydrostatics in the Circulation, Applications of the Bernoulli Equation Rigid Tube Flow Models Estimation of Entrance Length and Its Effect on Flow Development in Arteries Flow in Collapsible Vessels Unsteady Flow and Nonuniform Geometric Models Windkessel Models for the Human Circulation Continuum Models for Pulsatile Flow Dynamics, Hemodynamic Theories of Atherogenesis Wall Shear Stress and Its Effect on Endothelial Cells Flow through Curved Arteries and Bifurcations, Flow through Arterial Stenoses and Aneurysms Native Heart Valves. Aortic and Pulmonary Valves, Mitral and Tricuspid Valves Prosthetic Heart Valve Dynamics Brief History of Heart Valve Prostheses, Hemodynamic Assessment of Prosthetic Heart Valves In Vitro Studies of Coagulation Potential and Blood Damage Durability of Prosthetic Heart Valves, Current Trends in Valve Design Vascular Therapeutic Techniques |
Learning outcomes |
Upon completion of the course, students will:
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General Competences |
Critical Thinking: Analyze and evaluate complex fluid mechanics concepts in the context of biofluid dynamics.
Problem-Solving: Address challenges in blood flow analysis and physiological fluid dynamics using appropriate mathematical and computational techniques. Quantitative and Analytical Skills: Apply advanced mathematical and statistical methods to analyze fluid behavior and interpret experimental data. Scientific Inquiry: Formulate research questions, design experiments, and contribute to knowledge advancement in biofluid mechanics |